San Marco Vacations from $352

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Your San Marco Vacation

Avoid the hassle of travel planning with a San Marco vacation package. With all the details locked in before you take off, all you have to do is enjoy this leafy neighborhood's bars and pubs, cafes and culture. Your trip to San Marco wouldn't be complete without stopping by popular attractions nearby such as Orange Park Place Shopping Center, Theatre Jacksonville and Fort Caroline Shopping Center. Stop daydreaming and start doing. When it's time to lock in your ideal vacation to San Marco, Expedia will help get you there.

The Latest San Marco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Amelia Hotel at the Beach

Amelia Hotel at the Beach

Save 100% on your flight
$352
per person
Nov 27 - Dec 2
found 20 hours ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
8.6/10 Excellent! (2,276 reviews)
Hammock Beach Golf Resort & Spa

Hammock Beach Golf Resort & Spa

Save 100% on your flight
$458
per person
Nov 20 - Nov 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
8.8/10 Excellent! (1,008 reviews)
Too many lovebirds. Looked like hotel could use maintenance. Food was ok but priced high and wasn’t worth it

Reviewed on Sep 13, 2026

Landing Apartments near Downtown Jacksonville

Landing Apartments near Downtown Jacksonville

Downtown Jacksonville
Save 100% on your flight
$534
per person
Nov 27 - Dec 2
found 22 hours ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
No reviews
Close to ball. Park. Convenient parking

Reviewed on Sep 3, 2026

Landing Apartments Downtown Palm Coast

Landing Apartments Downtown Palm Coast

Town Center
Save 100% on your flight
$581
per person
Nov 27 - Dec 2
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
9.6/10 Exceptional! (4 reviews)
The apartment was clean and fresh! Beds are great and plenty of room for personal belongings. The people upstairs were loud walkers and this was a bit annoying in the evenings when trying to get to sleep. Also, the building light attached to the wall outside the master bedroom makes it impossible to make the bedroom dark with the blinds. Highly recommend getting that solved. Super new, clean, and comfy outside these things.

Reviewed on Sep 1, 2026

Hoyt House Amelia Island

Hoyt House Amelia Island

Fernandina Beach Historic District
Save 100% on your flight
$507
per person
Nov 20 - Nov 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Jacksonville (JAX)
9.4/10 Exceptional! (588 reviews)

Where to stay in San Marco

Find the best San Marco areas and neighborhoods for the activities you enjoy most. Learn more about San Marco
A city skyline with modern skyscrapers, a prominent Wells Fargo building, and a blue bridge over a river.

Downtown Jacksonville

2 out of top 10 points of interest in this area

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

A coastal town at dusk with a prominent clock tower, waterfront, and illuminated buildings.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

A sunset over a beach with waves and a pier.

Oceanfront

1 out of top 10 points of interest in this area

If you're spending some time in Oceanfront, Oceanfront Park and Northeast Florida Beaches are top sights worth seeing.

A river with a bridge, a marina with boats, and a city skyline with high-rise buildings.

Southside

1 out of top 10 points of interest in this area

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

A golf course with a pond, trees, and buildings in the background.

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

San Marco Hotel Deals

Scottish Inn Jacksonville Downtown

Scottish Inn Jacksonville Downtown

2300 Phillips Hwy Jacksonville FL
Fully refundableReserve now, pay when you stay
$41 nightly
$46 total
Sep 15 - Sep 16
Total with taxes and fees
Scottish Inn Jacksonville Downtown
Hilton Garden Inn Jacksonville Downtown Southbank

Hilton Garden Inn Jacksonville Downtown Southbank

1201 Kings Avenue Jacksonville FL
Fully refundableReserve now, pay when you stay
$117 nightly
$133 total
Sep 20 - Sep 21
Total with taxes and fees
8.4/10 Very Good! (1,003 reviews)
"Biggest problem was locating the entrance at night. The hotel shares an entrance and parking lot with a city owned lot. Apple Maps gave suboptimal directions. Staff at check-in were extremely helpful. Our plane was two hours late, and most restaurants were closed. The hotel restaurant was able to ..."

Reviewed on Sep 13, 2026

Hilton Garden Inn Jacksonville Downtown Southbank
Homewood Suites by Hilton Jacksonville Downtown-Southbank

Homewood Suites by Hilton Jacksonville Downtown-Southbank

1201 Kings Avenue Jacksonville FL
Fully refundableReserve now, pay when you stay
$130 nightly
$148 total
Sep 20 - Sep 21
Total with taxes and fees
8.6/10 Excellent! (888 reviews)
"Nice hotel.The rooms are big and spacious."

Reviewed on Sep 13, 2026

Homewood Suites by Hilton Jacksonville Downtown-Southbank
See all 3,069 properties in San Marco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular San Marco attractions

Theatre Jacksonville

You can make plans for a show at Theatre Jacksonville during your trip to Jacksonville. Amble around this vibrant area's riverfront or attend a sporting event.
See properties

Jack Rabbits Live

You can enjoy a show at Jack Rabbits Live on your trip to Jacksonville. Attend a sporting event in this family-friendly area, or simply enjoy its bars.
See properties

Things to do

Half-Day City Tour in Downtown Jacksonville

Half-Day City Tour in Downtown Jacksonville

$114
per adult
100% of travellers recommend
Half-Day City Tour in Downtown Jacksonville
1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports

1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports

$145
per traveler
90% of travellers recommend
1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports
The Escape Game at St. John's Town Center in Jacksonville

The Escape Game at St. John's Town Center in Jacksonville

$42
per adult
100% of travellers recommend
The Escape Game at St. John's Town Center in Jacksonville
See all activities in Jacksonville

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.